Antioxidant Effectiveness Test of Kapok Leaf Extract Moisturizer (Ceiba Pentandra (L.) Gaertn.) with DPPH Method

Authors

  • Afidatul Muadifah STIKES Karya Putra Bangsa
  • Dara Pranidya Tilarso Department of Pharmacy, STIKES Karya Putra Bangsa, Tulungagung, Indonesia
  • Amalia Eka Putri Department of Pharmacy, STIKES Karya Putra Bangsa, Tulungagung, Indonesia
  • Momodou Salieu Sowe Departement of Chemistry, University of The Gambia, Gambia

DOI:

https://doi.org/10.22437/chp.v8i1.33234

Keywords:

Antioxidant, DPPH Method, Kapok Leaves, Moisturizer

Abstract

Dry skin can often cause psychological discomfort. Moisturizer is a preparation that is used to improve dry skin. Kapok plant (Ceiba pentandra L. Gaertn) can be used as an active ingredient of moisturizer and can be used as a treatment, where the chemical content in kapok leaves are flavonoids, saponins, alkaloids, phenolic compounds, tannins and terpenoids as antioxidants. This study aims to determine the antioxidant activity of kapok leaf extract and moisturizer preparations with DPPH method using UV-Vis spectrophotometer, physical quality of preparations and antioxidant activity of moisturizer preparations using DPPH method. Kapok leaf extract was made in various concentrations, namely 20 ppm, 40 ppm and 60 ppm. The IC50 value of kapok leaf extract is 67.4007 ppm which has strong antioxidant activity. Then variations in the concentration of kapok leaf extract were put into the formulation of moisturizer preparations, the results of moisturizer preparations of kapok leaf extract and vitamin C met the requirements of the physical quality test. The moisturizer preparation was continued and tested for antioxidant activity using the DPPH method with ascorbic acid as a comparison. The results of the IC50 value on the kapuk leaf extract moisturizer preparation are 110.065 ppm which is classified as having moderate antioxidant activity and while the vitamin C moisturizer preparation is 9.8417 ppm which is classified as having very strong antioxidant activity.

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Author Biographies

Dara Pranidya Tilarso, Department of Pharmacy, STIKES Karya Putra Bangsa, Tulungagung, Indonesia

Department of Pharmacy, STIKES Karya Putra Bangsa, Tulungagung, Indonesia

Amalia Eka Putri, Department of Pharmacy, STIKES Karya Putra Bangsa, Tulungagung, Indonesia

Department of Pharmacy, STIKES Karya Putra Bangsa, Tulungagung, Indonesia

Momodou Salieu Sowe, Departement of Chemistry, University of The Gambia, Gambia

Departement of Chemistry, University of The Gambia, Gambia

References

Sari, B. H., & Diana, V. E. (2017). Formulasi Ekstrak Daun Pegagan (Centella asiatica) sebagai sediaan sabun cair. Jurnal Dunia Farmasi, 2(1), 40-49.

Salsabila, S., Rahmiyani, I., & Zustika, D. S. (2021). Nilai Sun Protection Factor (SPF) pada Sediaan Lotion Ekstrak Etanol Daun Jambu Air (Syzygium aqueum). Majalah Farmasetika, 6, 123-132.

B. M. Aaron. (2001). In: “Smith J (ed) The rise of modern genomics, 3rd ed”. Wiley, New York.

Ekayanti, N. L. P. S., Darsono, F. L., & Wijaya, S. (2019). Formulasi sediaan krim pelembab ekstrak air buah semangka (Citrullus lanatus). Jurnal Farmasi Sains dan Terapan, 6(1), 38-45.

Siva, J., & Afriadi, A. (2018). Formulasi Gel dari Sari Buah Strawberry (Fragaria X ananassa Duchesne) sebagai Pelembab Alami. Jurnal Dunia Farmasi, 3(1), 9-15.

Susanty, S., Ridnugrah, N. A., Chaerrudin, A., & Yudistirani, S. A. (2019). Aktivitas antioksidan ekstrak daun kelor (Moringa oleifera) sebagai zat tambahan pembuatan moisturizer. Prosiding Semnastek.

Busman, B., Edrizal, E., & Saputra, D. E. (2015). Uji aktivitas antibakteri ekstrak daun kapuk randu (Ceiba Pentandra (L.) Gaertn) terhadap bakteri Streptococcus Mutans. B-Dent: Jurnal Kedokteran Gigi Universitas Baiturrahmah, 2(1), 10-15.

[8] Yamin, Y., Hamsidi, R., Nasria, N., & Sabarudin, S. (2019). Karakterisasi dan Uji Aktivitas Antioksidan serta Penetapan Kadar Fenolik Total Ekstrak Etanol Kulit Batang Kapuk Randu (Ceiba pentandra L. Gaertn). Pharmauho: Jurnal Farmasi, Sains, Dan Kesehatan, 4(2), 2-5.

Fauziah, S., & Sari, N. P. (2020). Uji Aktivitas Antioksidandan Penetapan Kadar Flavonoid Totaldari Ekstrak Etanol 70% Daun Kapuk Randu (CEIBA PENTANDRA (L.) GEARTN) Dengan Metode DPPH. ISTA Online Technologi Journal, 1(1), 10-16.

Yumas, M. (2016). Formulasi Sediaan Krim Wajah Berbahan Aktif Ekstra Metanol Biji Kakao Non Fermentasi (Theobroma Cacao L) Kombinasi Madu Lebah. Jurnal Industri Hasil Perkebunan, 11(2), 75-87.

Damanis, F. V., Wewengkang, D. S., & Antasionasti, I. (2020). Uji Aktivitas Antioksidan Ekstrak Etanol Ascidian Herdmania Momus Dengan Metode DPPH (1, 1-Difenil-2-Pikrilhidrazil). Pharmacon, 9(3), 464-469.

Yimcharoen, M., Kittikunnathum, S., Suknikorn, C., Nak-On, W., Yeethong, P., Anthony, T. G., & Bunpo, P. (2019). Effects of ascorbic acid supplementation on oxidative stress markers in healthy women following a single bout of exercise. Journal of the International Society of Sports Nutrition, 16(1), 2.

Kemenkes, R. I. (2017). Farmakope Herbal Indonesia Edisi II. Jakarta: Kementrian Kesehatan RI.

Tutik, N. F., Junova, H., & Anatasia, I. (2021). Formulasi Sediaan Gel Moisturizer Anti-Aging Ekstrak Kulit Bawang Merah (Alliium cepa L.) Sebagai Antioksidan.

Budiyanto, A. (2015). Potensi Antioksidan, Inhibitor Tirosinase, dan Nilai Toksisitas dari Beberapa Spesies Tanaman Mangrove di Indonesia. Bogor: Intitute Pertanian Bogor.

Sawiji, R. T., & La, E. O. J. (2022). Formulasi Dan Uji Aktivitas Antioksidan Sediaan Body Butter Ekstrak Etanol Umbi Bit (Beta vulgaris L.) Dengan Metode DPPH. Jurnal Ilmiah Manuntung, 8(1), 173-180

Wardani, T. S., & Ria, S. (2020). Uji aktivitas antioksidan dengan metode dpph dan uji sitotoksik terhadap sel kanker payudara t47d pada ekstrak daun kemangi. Jurnal Farmasetis, 9(1), 51-64.

Rahmayani, U., Pringgenies, D., & Djunaedi, A. (2013). Uji aktivitas antioksidan ekstrak kasar keong bakau (Telescopium telescopium) dengan pelarut yang berbeda terhadap metode DPPH (diphenyl picril hidrazil). Journal of Marine Research, 2(4), 36-45

Kaban, V. E., Nasri, N., Syahputra, H. D., Fitri, R., Rani, Z., & Lubis, M. F. (2022). Formulasi Sediaan Gel dari Ekstrak Metanol Biji Alpukat (Persea americana Mill.) Sebagai Penyembuh Luka Sayat Pada Tikus Jantan (Rattus norvegicus). Herbal Medicine Journal, 5(2), 12-18.

Astuti, S. B., Lestari, T., & Nurviana, V. (2022). Formulasi gel facial wash ekstrak daun hantap (Sterculia coccinea Var. Jack) dan uji aktivitasnya sebagai antioksidan. In Prosiding Seminar Nasional Diseminasi Hasil Penelitian Program Studi S1 Farmasi (Vol. 1, No. 1).

Mulyani, T., Ariyani, H., Rahimah, & Rahmi, S. (2018). Formulasi dan aktifitas antioksidan lotion ekstrak daun suruhan (Peperomia pellucida L.). Journal of Current Pharmaceutical Sciences, 2(1), 111–117.

Faridi, A., Susilawaty, A., Rahmiati, B. F., Sianturi, E., Adiputra, I. M. S., Budiastutik, I., ... & Hulu, V. T. (2021). Metodologi Penelitian Kesehatan.

Rasydy, L. O. A., Zaky, M., & Surtiana, R. (2021). Formulasi dan Evaluasi Fisik Sediaan Hand Body Lotion Ekstrak Etanol Daun Miana (Pleactranthus scutellarioides (L.) R. Br.). Pharmauho: Jurnal Farmasi, Sains, Dan Kesehatan, 7(1), 33–38.

Husnani, & Muazham, M. F. Al. (2017). Optimasi Parameter Fisik Viskositas, Daya Sebar Dan Daya Lekat Pada Basis Natrium CMC DAN Carbopol 940 Pada Gel Madu Dengan Metode Simplex Lattice Design. Akademi Farmasi Yarsi Pontianak, 11–18.

Nakhil, U., Kaltsum, U., Purwojati, N., & Latifah, E. (2018). Uji Stabilitas dan Penentuan Formula Optimum pada Gel Madam” Gel Ekstrak Daun Adam Hawa (Rheo Discolor) sebagai Gel Antiinflamasi” untuk Penelitian Lanjutan. In Prosiding APC (Annual Pharmacy Conference) (Vol. 3, No. 1).

Putri, W. E., & Anindhita, M. A. (2022). Optimization of cardamom fruit ethanol extract gel with combination of HPMC and Sodium Alginate as the gelling agent using Simplex Lattice Design. Jurnal Ilmiah Farmasi, 107-120.

Ramadon, D., Septiani, R. M., Putri, S. N., & Mun'im, A. (2021). Pengaruh Antioksidan dan Kombinasi Pengawet terhadap Stabilitas Ekstrak Cair NADES Biji Kopi Hijau. JFIOnline| Print ISSN 1412-1107| e-ISSN 2355-696X, 13(2), 129-145.

Rowe R.C, P.J, Sheskey, & M.E, Q, (2009). Handbook of pharmaceutical Excipients, sixth edition. USA: Pharmaceutical Press

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Published

2024-06-30

How to Cite

Afidatul Muadifah, Tilarso, D. P. ., Putri, A. E., & Sowe, M. S. (2024). Antioxidant Effectiveness Test of Kapok Leaf Extract Moisturizer (Ceiba Pentandra (L.) Gaertn.) with DPPH Method. Chempublish Journal, 8(1), 1-10. https://doi.org/10.22437/chp.v8i1.33234