- Uji Efektivitas Daun Kelor Terhadap Shigella Dysenteriae: Uji Efektivitas Daun Kelor Terhadap Shigella Dysenteriae

Mellinia Alpatri Br Karo; Fransiska Ferdinanda; Oliviti Natali; Sri Wahyun  Nasution

doi:10.22437/biospecies.v14i1.11222

Authors

Mellinia Alpatri Br Karo Universitas Prima Indonesia
Fransiska Ferdinanda Universitas Prima Indonesia
Oliviti Natali Universitas Prima Indonesia
Sri Wahyun Nasution Universitas Prima Indonesia

DOI:

https://doi.org/10.22437/biospecies.v14i1.11222

Keywords:

diarrhea, shigella dysenteriae, Moringa leaf extract (Moringa oleifera Lamk), disc diffusion, inoculation

Abstract

Diarrheal disease is a disease that often occurs in developing countries and one of the factors causing the incidence of diarrhea is the bacteria Shigella dysenteriae. Moringa oleifera Lamk leaves contain alkaloid compounds, tannins, saponins, flavonoids, triterpenes / steroids, and polyphenols which are reported to have high antimicrobial and antioxidant activity. This study aims to measure the effectiveness of Moringa oleifera Lamk leaf extract in inhibiting the growth of Shigella dysentriae. This study uses a Post-Test Only Control Group Design research design and uses the disc diffusion method where the extract on MHA media has been inoculated with Shigella dysentriae bacteria. The data taken is primary data, namely the inhibition zone formed at a concentration of 15%, 30%, 45 %, 60%, 75%. The test results have shown that Moringa oleifera Lamk leaves can inhibit bacteria at a concentration of 75% with an average inhibition zone of 91.1 mm.